71308-34-4
71308-34-4
Chemical Structure
AG 1406
- CAS 番号: 71308-34-4
- Formula:C16H18N2O
- Molecular Weight:254.33
IUPAC Name: 2-(4-hydroxy-3,5-diisopropylbenzylidene)malononitrile
InChIKey: JSDJFOADLLJFQX-UHFFFAOYSA-N
SMILES: N#C/C(C#N)=C/C1=CC(C(C)C)=C(O)C(C(C)C)=C1
Biological Activity: AG 1406 (compound M19) is a HER2 inhibitor, with an IC50 of 10.57 μM for HER2 in BT474 cell and >50 μM for EGFR in EGF-3T3 cell[1].
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AG 1406 | 99.03% | AG 1406 (compound M19) is a HER2 inhibitor, with an IC50 of 10.57 μM for HER2 in BT474 cell and >50 μM for EGFR in EGF-3T3 cell. | ||||||||||||||||||||
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