72063-39-9
72063-39-9
Chemical Structure
Spinosin
- CAS No.: 72063-39-9
- Formula:C28H32O15
- Molecular Weight:608.54
IUPAC Name: 6-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
InChIKey: VGGSULWDCMWZPO-ODEMIOGVSA-N
SMILES: COC1=C([C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H]2O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO)C(O)=C4C(OC(C5=CC=C(O)C=C5)=CC4=O)=C1
Biological Activity: Spinosyn is a kind of effective C-saccharide, which has a protective effect. Spinosyn is active through Nrf2/HO-1 pathway inhibition Aβ1-42's production and combination[1][2][3 ].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Spinosin | 99.73% | Spinosyn is a kind of effective C-saccharide, which has a protective effect. Spinosyn is active through Nrf2/HO-1 pathway inhibition Aβ1-42's production and combination[3 ]. | ||||||||||||||||||||
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Spinosin (Standard) | ≥98% | Spinosin (Standard) is the analytical standard of Spinosin. This product is intended for research and analytical applications. Spinosyn is a kind of effective C-saccharide, which has a protective effect. Spinosyn is active through Nrf2/HO-1 pathway inhibition Aβ1-42's production and combination. | ||||||||||||||||||||
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Isovitexin 2′′-O-rhamnoside | 99.98% | Isovitexin 2′′-O-rhamnoside, a phenolic, has antioxidant and antiproliferative activities. | ||||||||||||||||||||
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Isomargaritene | Isomargaritene is a natural product. | |||||||||||||||||||||
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2''-O-Rhamnosylswertisin | 2''-O-Rhamnosylswertisin is a flavonoid product that can be isolated from Aleurites moluccanus. | |||||||||||||||||||||
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Embinin | Embinin is a natural product that can be isolated from Petals of Iris germanica Linnaeous. Embinin can enhance lumbar disc neovascularization and induces apoptosis of nucleus pulposus cells in lumbar disc herniation rats. | |||||||||||||||||||||
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Swertiajaponin 2''-O-rhamnoside | Swertiajaponin 2''-O-rhamnoside (2''-O-Rhamnosylswertiajaponin) is a natural flavonoid. | |||||||||||||||||||||
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(E)-6'''-Feruloylspinosin | (E)-6'''-Feruloylspinosin (Compound 3) is a flavonoid found in the seeds of Ziziphus jujuba Mill var. spinosa. (E)-6'''-Feruloylspinosin is a rotatable isomer of 6'''-Feruloylspinosin (HY-N2160). | |||||||||||||||||||||
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Saponarin (Standard) | ≥98% | Saponarin (Standard) is the analytical standard of Saponarin (HY-N5083). This product is intended for research and analytical applications. Saponarin is an orally active flavonoid compound. Saponarin can be isolated from Gypsophila trichotoma. Saponarin inhibits ERK/p38, NF-κB and MAPK phosphorylation and activates AMPK. Saponarin reduces IL-1β and COX-2. Saponarin has antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic and hypotensive effects. Saponarin improves sleep disorders. | ||||||||||||||||||||
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Isovitexin 2''-O-arabinoside | 99.49% | Isovitexin 2''-O-arabinoside is a flavonoid in plantlets of Avena sativa L.. | ||||||||||||||||||||
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Meloside A | 98.72% | Meloside A (Isovitexin 2''-O-glucoside) is a flavonoid with antioxidant activity. Meloside A can inhibit cell apoptosis and ROS production. Meloside A can inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Meloside A can reduce IL-6, TGF-β1 and DKK-1 levels. Meloside A can be used for the researches of inflammation and endocrinology, such as hair loss. | ||||||||||||||||||||
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Isoscoparin-2′′O-glucoside | 99.27% | Isoscoparin-2′′O-glucoside is a flavonoid that can be found in yellow grain mutant of rice. Isoscoparin-2′′O-glucoside shows antioxidant activity. | ||||||||||||||||||||
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References
- [1]. Jung IH, et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice. Pharmacol Biochem Behav. 2014 May;120:88-94. [Content Brief]
- [2]. Zhang X, et al. Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway. Biomol Ther (Seoul). 2019 Dec 3. [Content Brief]
