7403-44-3
Chemical Structure
P18IN005 hydrochloride
- CAS No.: 7403-44-3
- Formula:C19H24ClNO2
- Molecular Weight:333.85
IUPAC Name: 2-(butylamino)-1-(4-methoxyphenyl)-2-phenylethan-1-one hydrochloride
InChIKey: ADMJIDODCQLGIZ-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C(C(C2=CC=CC=C2)NCCCC)=O.Cl
Biological Activity: P18IN005 hydrochloride is a novel inhibitor of p18, exhibiting potent activity in negatively regulating haematopoietic stem cell (HSC) self-renewal. P18IN005 hydrochloride has been shown to be more effective than p27 in inhibiting HSC self-renewal in mouse models. P18IN005 hydrochloride promotes the expansion of functional HSCs in short-term cultures. P18IN005 hydrochloride serves as a valuable tool for dissecting the signaling pathways involved in stem cell self-renewal.
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P18IN005 hydrochloride | P18IN005 hydrochloride is a novel inhibitor of p18, exhibiting potent activity in negatively regulating haematopoietic stem cell (HSC) self-renewal. P18IN005 hydrochloride has been shown to be more effective than p27 in inhibiting HSC self-renewal in mouse models. P18IN005 hydrochloride promotes the expansion of functional HSCs in short-term cultures. P18IN005 hydrochloride serves as a valuable tool for dissecting the signaling pathways involved in stem cell self-renewal. | |||||||||||||||||||||
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