74135-10-7
Chemical Structure
Sucrose octasulfate sodium
- CAS No.: 74135-10-7
- Formula:C12H14Na8O35S8
- Molecular Weight:1158.66
IUPAC Name: sodium (2R,3R,4S,5R,6R)-2-(((2S,3S,4R,5R)-3,4-bis(sulfonatooxy)-2,5-bis((sulfonatooxy)methyl)tetrahydrofuran-2-yl)oxy)-6-((sulfonatooxy)methyl)tetrahydro-2H-pyran-3,4,5-triyl tris(sulfate)
InChIKey: CPRSOZZDECJZKH-QRDGSJRXSA-F
SMILES: O=[S](OC[C@]([C@H]([C@@H]1O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)(O[C@@H]1CO[S](=O)(O[Na])=O)O[C@@H](O[C@@H]2CO[S](=O)(O[Na])=O)[C@@H]([C@H]([C@@H]2O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)(O[Na])=O
Biological Activity: Sucrose octasulfate sodium, a derivative of sulfated oligosaccharides, is a matrix metalloproteinase (MMP) inhibitor. Sucrose octasulfate sodium stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach by acting directly on D cells in the gastric mucosa. Sucrose octasulfate sodium exerts its ulcer-healing effect by releasing endogenous gastric somatostatin. Sucrose octasulfate sodium can be used as a pharmaceutical excipient and significantly improves wound closure in diabetic foot ulcers caused by nerve ischemia and venous leg ulcers. Sucrose octasulfate sodium can be used in the study of chronic wound healing[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sucrose octasulfate sodium | 98.0% | Sucrose octasulfate sodium, a derivative of sulfated oligosaccharides, is a matrix metalloproteinase (MMP) inhibitor. Sucrose octasulfate sodium stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach by acting directly on D cells in the gastric mucosa. Sucrose octasulfate sodium exerts its ulcer-healing effect by releasing endogenous gastric somatostatin. Sucrose octasulfate sodium can be used as a pharmaceutical excipient and significantly improves wound closure in diabetic foot ulcers caused by nerve ischemia and venous leg ulcers. Sucrose octasulfate sodium can be used in the study of chronic wound healing. | ||||||||||||||||||||
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- [1]. Edmonds M, et al. Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial. Lancet Diabetes Endocrinol. 2018;6(3):186-196. [Content Brief]
- [2]. Lucey MR, et al. Sucrose octasulfate stimulates gastric somatostatin release. Am J Med. 1991;91(2A):52S-57S. [Content Brief]
Keywords
