747408-78-2
747408-78-2
Chemical Structure
PBT 1033
Synonym(s): PBT 2
- CAS No.: 747408-78-2
- Formula:C12H12Cl2N2O
- Molecular Weight:271.15
IUPAC Name: 5,7-dichloro-2-((dimethylamino)methyl)quinolin-8-ol
InChIKey: YZPOQCQXOSEMAZ-UHFFFAOYSA-N
SMILES: ClC1=CC(Cl)=C(O)C2=C1C=CC(CN(C)C)=N2
Biological Activity: PBT 1033 (PBT 2) is an orally active copper/zinc ionophore. PBT 1033 restores cognition in mouse models of Alzheimer's disease (AD). PB 1033 also has antibacterial activity against Gram-positive bacteria[1][2].
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PBT 1033 | 99.35% | PBT 1033 (PBT 2) is an orally active copper/zinc ionophore. PBT 1033 restores cognition in mouse models of Alzheimer's disease (AD). PB 1033 also has antibacterial activity against Gram-positive bacteria. | ||||||||||||||||||||
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PBT 1033 (Standard) | ≥98% | PBT 1033 (Standard) is the analytical standard of PBT 1033. This product is intended for research and analytical applications. PBT 1033 (PBT 2) is an orally active copper/zinc ionophore. PBT 1033 restores cognition in mouse models of Alzheimer's disease (AD). PB 1033 also has antibacterial activity against Gram-positive bacteria. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-105321APBT 1033 hydrochloride -
Similarity Score 0.59
HY-120475BPBT434 free base -
Similarity Score 0.58
HY-120475PBT434 -
Similarity Score 0.58
HY-W7284487,8-Dihydroxykynurenate -
Similarity Score 0.58
HY-1008345,7-Dichlorokynurenic acid -
Similarity Score 0.58
HY-171274DOCK5-IN-1 -
Similarity Score 0.57
HY-W0115816,9-Dichloro-2-methoxyacridine -
Similarity Score 0.57
HY-100834A5,7-Dichlorokynurenic acid sodium -
Similarity Score 0.56
HY-137563A2793 -
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