762-29-8
Chemical Structure
Farnesylacetone
- CAS No.: 762-29-8
- Formula:C18H30O
- Molecular Weight:262.44
IUPAC Name: (5E,9E)-6,10,14-trimethylpentadeca-5,9,13-trien-2-one
InChIKey: LTUMRKDLVGQMJU-IUBLYSDUSA-N
SMILES: O=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
Biological Activity: Farnesylacetone acts as a transcriptional regulator, RNA synthesis modulator, and male hormone. Farnesylacetone can be extracted from the androgenic glands of the green crab (Carcinus maenas). Farnesylacetone modulates transcriptional processes, inhibits uridine incorporation into all types of RNA and leucine incorporation into ovaries, while stimulating uridine incorporation into tRNA/poly (A)+ RNA and leucine incorporation into testes. It suppresses electron transport in mitochondrial Complex I and Complex II. Farnesylacetone inhibits vitellogenesis in crustacean ovaries and stimulates uridine incorporation in crustacean intestines. It functions as an androgen in crustaceans[1][2].
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Farnesylacetone | Farnesylacetone acts as a transcriptional regulator, RNA synthesis modulator, and male hormone. Farnesylacetone can be extracted from the androgenic glands of the green crab (Carcinus maenas). Farnesylacetone modulates transcriptional processes, inhibits uridine incorporation into all types of RNA and leucine incorporation into ovaries, while stimulating uridine incorporation into tRNA/poly (A)+ RNA and leucine incorporation into testes. It suppresses electron transport in mitochondrial Complex I and Complex II. Farnesylacetone inhibits vitellogenesis in crustacean ovaries and stimulates uridine incorporation in crustacean intestines. It functions as an androgen in crustaceans. | |||||||||||||||||||||
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- [1]. Berreur-Bonnenfant J, et al. Comparative effect of farnesylacetone on macromolecular synthesis in gonads of crustaceans. General and comparative endocrinology. 1984 Jun;54(3):462-8. [Content Brief]
- [2]. Dupont J, et al. Farnesylacetone, a sesquiterpenic hormone of Crustacea, inhibits electron transport in isolated rat liver mitochondria. Biology of the cell. 1989;67(2):141-6. [Content Brief]
Keywords
