769933-15-5
769933-15-5
Chemical Structure
Biotin-aniline
- CAS No.: 769933-15-5
- Formula:C18H26N4O2S
- Molecular Weight:362.49
IUPAC Name: N-(4-aminophenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
InChIKey: AHRRICHWBPPWDZ-ZOBUZTSGSA-N
SMILES: NC(C=C1)=CC=C1CCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O
Biological Activity: Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline is also a novel APEX2 substrate. Biotin-aniline can label proteins via miniSOG. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity[1][2].
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Biotin-aniline | 99.63% | Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline is also a novel APEX2 substrate. Biotin-aniline can label proteins via miniSOG. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity. | ||||||||||||||||||||
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References
- [1]. Zhou Y, et al. Expanding APEX2 Substrates for Proximity-Dependent Labeling of Nucleic Acids and Proteins in Living Cells. Angew Chem Int Ed Engl. 2019;58(34):11763-11767. [Content Brief]
- [2]. Zheng F, et al. Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome. Nat Commun. 2023 May 23;14(1):2978. [Content Brief]
