77094-11-2
77094-11-2
Chemical Structure
Me-IQ
Synonym(s): Methyl-IQ
- CAS No.: 77094-11-2
- Formula:C12H12N4
- Molecular Weight:212.25
IUPAC Name: 3,4-dimethyl-3H-imidazo[4,5-f]quinolin-2-amine
InChIKey: GMGWMIJIGUYNAY-UHFFFAOYSA-N
SMILES: NC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3
Biological Activity: Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Me-IQ | 99.48% | Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
![2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine-<sup>13</sup>C Chemical Structure](//file.medchemexpress.com/product_pic/hy-w281364s.gif)
HY-W281364S2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine-13C -
Similarity Score 0.74
HY-W3561814,8-DiMeIQx -
Similarity Score 0.71
HY-W5858674,7,8-TriMeIQx -
Similarity Score 0.67
HY-W355129MeIQx -
Similarity Score 0.67
HY-W779191MeIQx-13C -
Similarity Score 0.64
HY-W3504477,8-DimeIQX -
Similarity Score 0.64
![2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d<sub>3</sub> Chemical Structure](//file.medchemexpress.com/product_pic/hy-w700103.gif)
HY-W7001032-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d3 -
Similarity Score 0.60
HY-W0045645,6-Diamino-1,10-phenanthroline -
Similarity Score 0.59
HY-119993AR03 -
Explore the MedChemAI to find more analogs
![2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine-<sup>13</sup>C Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w281364s.gif)
![2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d<sub>3</sub> Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w700103.gif)
References
- [1]. H Ohgaki, et al. Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. Princess Takamatsu Symp. 1985;16:97-105. [Content Brief]
- [2]. T Aune, et al. Mutagenic activation of IQ and Me-IQ by liver and lung microsomes from rabbit and mouse, and with isolated lung cells from the rabbit. Carcinogenesis. 1986 Feb;7(2):273-6. [Content Brief]
