77465-10-2
Chemical Structure
Adrenocorticotropic hormone (1-39), rat
Synonym(s): ACTH(1-39), rat
- CAS No.: 77465-10-2
- Formula:C210H315N57O57S
- Molecular Weight:4582.23
SMILES: O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(NCC(N[C@@H](CCCCN)C(N6[C@@H](CCC6)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N7[C@@H](CCC7)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC8=CC=C(C=C8)O)C(N9[C@@H](CCC9)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC%10=CC=CC=C%10)C(N%11[C@@H](CCC%11)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC%12=CC=CC=C%12)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Biological Activity: Adrenocorticotropic hormone (1-39), rat (ACTH (1-39), rat) is a melanocortin receptor agonist targeting MC4-R that binds to and activates MCRs. Adrenocorticotropic hormone (1-39), rat reduces the proportion of apoptosis after excitotoxicity- or inflammation-related injury. Adrenocorticotropic hormone (1-39), rat can be used in research on multiple sclerosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Adrenocorticotropic hormone (1-39), rat | 99.31% | Adrenocorticotropic hormone (1-39), rat (ACTH (1-39), rat) is a melanocortin receptor agonist targeting MC4-R that binds to and activates MCRs. Adrenocorticotropic hormone (1-39), rat reduces the proportion of apoptosis after excitotoxicity- or inflammation-related injury. Adrenocorticotropic hormone (1-39), rat can be used in research on multiple sclerosis. | ||||||||||||||||||||
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Similarity Score 0.88
HY-P4864Biotinyl-ACTH (1-39) (human) -
Similarity Score 0.82
HY-P5757(D-Trp32)-Neuropeptide Y (porcine) -
Similarity Score 0.82
HY-P5203Enterocin K1 -
Similarity Score 0.81
HY-P5204Enterocin Hybrid 1 -
Similarity Score 0.79
HY-P1727Super-TDU -
Similarity Score 0.79
HY-P4790Acetyl-Exenatide -
Similarity Score 0.79
HY-103545GIP (1-39) -
Similarity Score 0.78
HY-P4874ACTH (7-38) (human) -
Similarity Score 0.78
HY-P4459(Des-Gly2)-Exenatide -
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References
- [1]. Schulz C, et al. Endogenous ACTH, not only alpha-melanocyte-stimulating hormone, reduces food intake mediated by hypothalamic mechanisms. Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E237-44.
- [2]. Lisak RP, et al. Melanocortin receptor agonist ACTH 1-39 protects rat forebrain neurons from apoptotic, excitotoxic and inflammation-related damage. Experimental neurology. 2015 Nov;273:161-7. [Content Brief]
