776-56-7
776-56-7
Chemical Structure
5-Fluoro-α-methyltryptamine hydrochloride
- CAS No.: 776-56-7
- Formula:C11H14ClFN2
- Molecular Weight:228.69
IUPAC Name: 1-(5-fluoro-1H-indol-3-yl)propan-2-amine hydrochloride
InChIKey: RVHBLKWBRZWGLS-UHFFFAOYSA-N
SMILES: FC1=CC2=C(NC=C2CC(C)N)C=C1.Cl
Biological Activity: 5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively[1][2].
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5-Fluoro-α-methyltryptamine hydrochloride | 5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively. | |||||||||||||||||||||
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References
- [1]. N Chairungsrilerd, et al. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998 Mar;123(5):855-62. [Content Brief]
- [2]. Bruce E Blough, et al. Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4754-4758. [Content Brief]
