78263-90-8
78263-90-8
Chemical Structure
2-Methyl-5-HT
Synonym(s): 2-Methyl-5-hydroxytryptamine; 2-Methylserotonin; 2-Me-5-HT
- CAS No.: 78263-90-8
- Formula:C11H14N2O
- Molecular Weight:190.24
IUPAC Name: 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol
InChIKey: WYWNEDARFVJQSG-UHFFFAOYSA-N
SMILES: OC1=CC2=C(NC(C)=C2CCN)C=C1
Biological Activity: 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1].
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2-Methyl-5-HT | 98.93% | 2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects. | ||||||||||||||||||||
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References
- [1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84. [Content Brief]
