2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. DCAI

DCAI is Ras protein binder. DCAI can inhibit the Ras activation and nucleotide exchange mediated by SOS. DCAI can be used for the research of cancer associated with Ras mutations .

For research use only. We do not sell to patients.

DCAI

DCAI Chemical Structure

CAS No. : 299165-92-7

Size Price Stock
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO Ask For Quote & Lead Time
Solid
5 mg Ask For Quote & Lead Time
10 mg Ask For Quote & Lead Time
25 mg Ask For Quote & Lead Time
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DCAI Related Antibodies

Top Publications Citing Use of Products

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K-Ras H-Ras N-Ras Ras

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Description

DCAI is Ras protein binder. DCAI can inhibit the Ras activation and nucleotide exchange mediated by SOS. DCAI can be used for the research of cancer associated with Ras mutations [1].

Molecular Weight

243.13

Formula

C11H12Cl2N2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(NC1=C2C(Cl)=CC(Cl)=C1)=C2CCN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (171.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1130 mL 20.5651 mL 41.1303 mL
5 mM 0.8226 mL 4.1130 mL 8.2261 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1130 mL 20.5651 mL 41.1303 mL 102.8256 mL
5 mM 0.8226 mL 4.1130 mL 8.2261 mL 20.5651 mL
10 mM 0.4113 mL 2.0565 mL 4.1130 mL 10.2826 mL
15 mM 0.2742 mL 1.3710 mL 2.7420 mL 6.8550 mL
20 mM 0.2057 mL 1.0283 mL 2.0565 mL 5.1413 mL
25 mM 0.1645 mL 0.8226 mL 1.6452 mL 4.1130 mL
30 mM 0.1371 mL 0.6855 mL 1.3710 mL 3.4275 mL
40 mM 0.1028 mL 0.5141 mL 1.0283 mL 2.5706 mL
50 mM 0.0823 mL 0.4113 mL 0.8226 mL 2.0565 mL
60 mM 0.0686 mL 0.3428 mL 0.6855 mL 1.7138 mL
80 mM 0.0514 mL 0.2571 mL 0.5141 mL 1.2853 mL
100 mM 0.0411 mL 0.2057 mL 0.4113 mL 1.0283 mL
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DCAI Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DCAI299165-92-7RasInhibitorinhibitorinhibit

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