78441-46-0
Chemical Structure
ORF 17583
- CAS No.: 78441-46-0
- Formula:C13H21N5O2S2
- Molecular Weight:343.47
InChIKey: MLEQRRUOXXDANO-UHFFFAOYSA-N
SMILES: O=S1N=C(C(NCCSCC2=CC=C(CN(C)C)O2)=N1)NC
Biological Activity: ORF 17583 is a Ranitidine (HY-B0693) analogue and H2 receptor antagonist. ORF 17583 exhibits typical reversible competitive antagonism in the guinea pig right atria model, causing a dose-dependent rightward shift of the histamine concentration-response curve without reducing the maximum effect, and its action is fully reversible upon washing. ORF 17583 can be used for research on peptic ulcers and hyperacidity[1].
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ORF 17583 | ORF 17583 is a Ranitidine (HY-B0693) analogue and H2 receptor antagonist. ORF 17583 exhibits typical reversible competitive antagonism in the guinea pig right atria model, causing a dose-dependent rightward shift of the histamine concentration-response curve without reducing the maximum effect, and its action is fully reversible upon washing. ORF 17583 can be used for research on peptic ulcers and hyperacidity. | |||||||||||||||||||||
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Keywords
