79498-31-0
Chemical Structure
Glaucocalyxin A
- CAS No.: 79498-31-0
- Formula:C20H28O4
- Molecular Weight:332.43
IUPAC Name: (4aS,6R,6aR,9S,11aS,11bR,12R)-6,12-dihydroxy-4,4,11b-trimethyl-8-methylenedodecahydro-6a,9-methanocyclohepta[a]naphthalene-3,7-dione
InChIKey: UCDVIBNDYLUWFP-MJTHGBBVSA-N
SMILES: CC1(C)C(CC[C@@]2(C)[C@@]3([H])[C@@]4(C(C([C@H](CC3)[C@H]4O)=C)=O)[C@H](O)C[C@]12[H])=O
Biological Activity: Glaucocalyxin A, an ent-kauranoid diterpene from Rabdosia japonica var., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulating PI3K/Akt signaling pathway. Glaucocalyxin A has antitumor effect[1].
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Glaucocalyxin A | 99.88% | Glaucocalyxin A, an ent-kauranoid diterpene from Rabdosia japonica var., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulating PI3K/Akt signaling pathway. Glaucocalyxin A has antitumor effect. | ||||||||||||||||||||
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Keywords
