Glaucocalyxin D

Cat. No.: HY-N7205: FAQs
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Glaucocalyxin D is a ent-kauranoid-type diterpenoid that can be isolated from Rabdosia japonica. Glaucocalyxin D shows cytotoxicity against various human tumor cell lines. Glaucocalyxin D can be used for cancer research.

For research use only. We do not sell to patients.

Glaucocalyxin D Chemical Structure

CAS No. : 140671-02-9

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Description

In Vitro

Glaucocalyxin D (0-100 μM; 48 h) has strong cytotoxicity against four human tumor cell lines A549, CCRF-CEM, HCT116 and HL-60^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:	A549, CCRF-CEM, HCT116 and HL-60 cell lines
Concentration:	0-100 μM
Incubation Time:	48 hours
Result:	Showed cytotoxicity against A549, HCT116, CCRF-CEM and HL-60 cells with IC₅₀ values of 7.7, 6.04, 2.70 and 3 μM, respectively.

Molecular Weight

374.47

Formula

C₂₂H₃₀O₅

CAS No.

140671-02-9

SMILES

CC(O[C@H](C[C@]1([H])C2(C)C)[C@](C3O)(C4=O)[C@](CC[C@@]3([H])C4=C)([H])[C@@]1(CCC2=O)C)=O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liu HC, et al. Monomeric and dimeric ent-kauranoid-type diterpenoids from rabdosia japonica and their cytotoxicity and anti-HBV activities. Fitoterapia. 2017 Apr;118:94-100. [Content Brief]

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glaucocalyxin D140671-02-9Othersditerpenoidnatural compoundcytotoxicitycancerA549HCT116CCRF-CEMHL-60Inhibitorinhibitorinhibit

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