81-55-0

1,8-Dihydroxy-4,5-dinitroanthraquinone Chemical Structure
81-55-0

Chemical Structure

1,8-Dihydroxy-4,5-dinitroanthraquinone

Synonym(s): ARDP0006; DHDNE

  • CAS No.: 81-55-0
  • Formula:C14H6N2O8
  • Molecular Weight:330.21

IUPAC Name: 1,8-dihydroxy-4,5-dinitroanthracene-9,10-dione

InChIKey: GJCHQJDEYFYWER-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(C3=C(C=CC(O)=C13)[N+]([O-])=O)=O)C([N+]([O-])=O)=CC=C2O

Biological Activity: 1,8-Dihydroxy-4,5-dinitroanthraquinone (ARDP0006; DHDNE) is a potent inhibitor of serine proteinase NS2B/3, the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase activity and viral inhibition ability with IC50s of 432 μM and 4.2 μM, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 μM to 432 μM[1].

Cat. No. Product Name Purity Description Pricing
HY-121138 		1,8-Dihydroxy-4,5-dinitroanthraquinone 98.03% 1,8-Dihydroxy-4,5-dinitroanthraquinone (ARDP0006; DHDNE) is a potent inhibitor of serine proteinase NS2B/3, the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase activity and viral inhibition ability with IC50s of 432 μM and 4.2 μM, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 μM to 432 μM.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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