81635-83-8
81635-83-8
Chemical Structure
PAF antagonist-1
- CAS No.: 81635-83-8
- Formula:C20H25NO4S
- Molecular Weight:375.48
InChIKey: NPGXSXQWVRRLAU-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)NC(C)=C(C1C)C(OCCSC2=CC=CC=C2)=O)OCC
Biological Activity: PAF antagonist-1 is a platelet activating factor (PAF) receptor antagonist with a target Ki of 69 nM. PAF antagonist-1 inhibits PAF binding and displays enhanced affinity at A1, A2a, and A3 adenosine receptor subtypes compared to related dihydropyridine analogs with smaller ester groups. PAF antagonist-1 can be used for cardiovascular disorders, especially hypertension and coronary heart disease[1].
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PAF antagonist-1 | PAF antagonist-1 is a platelet activating factor (PAF) receptor antagonist with a target Ki of 69 nM. PAF antagonist-1 inhibits PAF binding and displays enhanced affinity at A1, A2a, and A3 adenosine receptor subtypes compared to related dihydropyridine analogs with smaller ester groups. PAF antagonist-1 can be used for cardiovascular disorders, especially hypertension and coronary heart disease. | |||||||||||||||||||||
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