852391-20-9
852391-20-9
Chemical Structure
Necrostatin 2 (S enantiomer)
- CAS No.: 852391-20-9
- Formula:C13H12ClN3O2
- Molecular Weight:277.71
IUPAC Name: (S)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione
InChIKey: WIKGAEMMNQTUGL-JTQLQIEISA-N
SMILES: O=C1N(C)C([C@H](CC2=CNC3=C2C=CC=C3Cl)N1)=O
Biological Activity: Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2 (HY-14622). Necrostatin 2 S enantiomer inhibits TNF-α-induced necroptosis in Jurkat T cells. Necrostatin 2 S enantiomer can be used for the research of ischemic brain injury (stroke)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Necrostatin 2 (S enantiomer) | 99.76% | Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2 (HY-14622). Necrostatin 2 S enantiomer inhibits TNF-α-induced necroptosis in Jurkat T cells. Necrostatin 2 S enantiomer can be used for the research of ischemic brain injury (stroke). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-14622Necrostatin 2 -
Similarity Score 1.00
HY-14622ARNecrostatin 2 racemate (Standard) -
Similarity Score 0.86
HY-168770Cl-Necrostatin-1 -
Similarity Score 0.83
HY-135826Necroptosis-IN-1 -
Similarity Score 0.72
HY-15760Necrostatin-1 -
Similarity Score 0.70
HY-W782635DL-5-Indolylmethylhydantoin -
Similarity Score 0.65
HY-121954Necrostatin-1 (inactive control) -
Similarity Score 0.62
HY-P2092Cyclo(L-leucyl-L-tryptophyl) -
Similarity Score 0.62
HY-N12900TDD -
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