85505-64-2
85505-64-2
Chemical Structure
Vapiprost
Synonym(s): GR 32191
- CAS No.: 85505-64-2
- Formula:C30H39NO4
- Molecular Weight:477.63
IUPAC Name: (Z)-7-((1R,2R,3S,5S)-5-([1,1'-biphenyl]-4-ylmethoxy)-3-hydroxy-2-(piperidin-1-yl)cyclopentyl)hept-4-enoic acid
InChIKey: GQGRDYWMOPRROR-XUSMOFMBSA-N
SMILES: OC(CC/C=C\CC[C@@H]1[C@@H](N2CCCCC2)[C@H](C[C@@H]1OCC3=CC=C(C4=CC=CC=C4)C=C3)O)=O
Biological Activity: Vapiprost (GR 32191) is a thromboxane A2 receptor (TXA2 Receptor) antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1×10-8 M[1].
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Vapiprost | Vapiprost (GR 32191) is a thromboxane A2 receptor (TXA2 Receptor) antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1×10-8 M. | |||||||||||||||||||||
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