85697-89-8
85697-89-8
Chemical Structure
L-NAPNA
- CAS No.: 85697-89-8
- Formula:C12H17N7O5
- Molecular Weight:339.31
IUPAC Name: (S)-2-amino-5-(3-nitroguanidino)-N-(4-nitrophenyl)pentanamide
InChIKey: LNWGWFVAPQTGMG-JTQLQIEISA-N
SMILES: O=C(NC1=CC=C([N+]([O-])=O)C=C1)[C@@H](N)CCCNC(N[N+]([O-])=O)=N
Biological Activity: L-NAPNA is a nitric oxide synthase (NOS) inhibitor with an IC50 of 1.4 μM. L-NAPNA exhibits analgesic effects by inhibiting formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and suppressing acetic acid-induced abdominal writhing in mice (ED50 of 25 mg/kg). L-NAPNA can be used in research related to central nervous system diseases[1].
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L-NAPNA | L-NAPNA is a nitric oxide synthase (NOS) inhibitor with an IC50 of 1.4 μM. L-NAPNA exhibits analgesic effects by inhibiting formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and suppressing acetic acid-induced abdominal writhing in mice (ED50 of 25 mg/kg). L-NAPNA can be used in research related to central nervous system diseases. | |||||||||||||||||||||
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