859142-95-3
859142-95-3
Chemical Structure
TDP1 Inhibitor-2
- CAS No.: 859142-95-3
- Formula:C25H14Cl2O5
- Molecular Weight:465.28
IUPAC Name: 7'-((2,6-dichlorobenzyl)oxy)-2H,2'H-[3,4'-bichromene]-2,2'-dione
InChIKey: QEOYHBDGERTIQV-UHFFFAOYSA-N
SMILES: ClC1=CC=CC(Cl)=C1COC2=CC=C(C(C3=CC(C=CC=C4)=C4OC3=O)=CC(O5)=O)C5=C2
Biological Activity: TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC50 of 3.5 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TDP1 Inhibitor-2 | 99.75% | TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC50 of 3.5 μM. | ||||||||||||||||||||
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