859142-95-3

TDP1 Inhibitor-2 Chemical Structure
859142-95-3

Chemical Structure

TDP1 Inhibitor-2

  • CAS No.: 859142-95-3
  • Formula:C25H14Cl2O5
  • Molecular Weight:465.28

IUPAC Name: 7'-((2,6-dichlorobenzyl)oxy)-2H,2'H-[3,4'-bichromene]-2,2'-dione

InChIKey: QEOYHBDGERTIQV-UHFFFAOYSA-N

SMILES: ClC1=CC=CC(Cl)=C1COC2=CC=C(C(C3=CC(C=CC=C4)=C4OC3=O)=CC(O5)=O)C5=C2

Biological Activity: TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC50 of 3.5 μM[1].

Cat. No. Product Name Purity Description Pricing
HY-147750 		TDP1 Inhibitor-2 99.75% TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC50 of 3.5 μM.
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