Spindlactone B
Spindlactone B (SPL-B) is a TACC3 inhibitor. Spindlactone B reduces the level of acetylated Microtubules. Spindlactone B can be used in the research of neurological diseases.
For research use only. We do not sell to patients.
- CAS No.: 1465248-60-5
- Formula: C27H22N2O5
- Molecular Weight:454.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Spindlactone B (0.25 µg/mL; 48 h) reduces somatic microtubule acetylation, neurite growth, and axon formation in primary mouse cortical neurons, while Cep120 overexpression partially reverses these effects[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1465248-60-5
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Molecular Weight 454.48
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Formula C27H22N2O5
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SMILES
O=C1OC2=C(C=CC(O)=C2CN(CC=3C=CN=CC3)CC)C(=C1)C4=CC=5C=CC=CC5OC4=O
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Synonyms
SPL-B
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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