865362-74-9
865362-74-9
Chemical Structure
FR 180204
- CAS No.: 865362-74-9
- Formula:C18H13N7
- Molecular Weight:327.34
IUPAC Name: 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine
InChIKey: XVECMUKVOMUNLE-UHFFFAOYSA-N
SMILES: NC1=NNC2=NN=C(C3=C4C=CC=CN4N=C3C5=CC=CC=C5)C=C21
Biological Activity: FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
FR 180204 | 99.91% | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.80
HY-112469ERK Inhibitor II (Negative control) -
Similarity Score 0.52
HY-146805EB1 -
Similarity Score 0.49
HY-78727Ibrutinib deacryloylpiperidine -
Similarity Score 0.48
HY-172676GW461484A -
Similarity Score 0.48
HY-168998Yck2-IN-1 -
Similarity Score 0.48
HY-171774PBRM1/SMARCA2,4-ligand-1 -
Similarity Score 0.47
HY-100933MY-5445 -
Similarity Score 0.47
HY-163943UNI418 -
Similarity Score 0.47
HY-112129AGI25696-analog -
Explore the MedChemAI to find more analogs
