86879-39-2
86879-39-2
Chemical Structure
CMPF
- CAS No.: 86879-39-2
- Formula:C12H16O5
- Molecular Weight:240.25
IUPAC Name: 2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid
InChIKey: WMCQWXZMVIETAO-UHFFFAOYSA-N
SMILES: O=C(O)CCC1=C(C(O)=O)C(C)=C(CCC)O1
Biological Activity: CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CMPF | 99.64% | CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice. | ||||||||||||||||||||
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CMPF-d5 | 99.0% | CMPF-d5 is the deuterium labeled CMPF. | ||||||||||||||||||||
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CMPF-d3 | CMPF-d3 is the deuterium labeled CMPF-d3 (HY-W654119). | |||||||||||||||||||||
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References
- [1]. Prentice KJ, et al. The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction. Cell Metab. 2014 Apr 1;19(4):653-66. [Content Brief]
- [2]. Prentice KJ, et al. CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. EBioMedicine. 2018 Jan;27:200-213. [Content Brief]
