9026-44-2
9026-44-2
Chemical Structure
Polyphosphate kinase
Synonym(s): RsPPK; PPK
- CAS No.: 9026-44-2
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Polyphosphate kinase]
Biological Activity: Polyphosphate kinase (RsPPK; PPK) is a key enzyme in bacteria that catalyzes the reversible conversion between inorganic polyphosphate (polyP) and nucleoside phosphates (ATP/ADP/AMP, etc.). Polyphosphate kinase antagonizes the expression of virulence genes regulated by (p) ppGpp, PigR, MglA and SspA in Francisella tularensis. Polyphosphate kinase can be used in studies related to tularemia[1][2].
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Polyphosphate kinase | Polyphosphate kinase (RsPPK; PPK) is a key enzyme in bacteria that catalyzes the reversible conversion between inorganic polyphosphate (polyP) and nucleoside phosphates (ATP/ADP/AMP, etc.). Polyphosphate kinase antagonizes the expression of virulence genes regulated by (p) ppGpp, PigR, MglA and SspA in Francisella tularensis. Polyphosphate kinase can be used in studies related to tularemia. | |||||||||||||||||||||
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References
- [1]. Neville N, et al. Polyphosphate Kinase 2 (PPK2) Enzymes: Structure, Function, and Roles in Bacterial Physiology and Virulence. Int J Mol Sci. 2022;23(2):670. Published 2022 Jan 8. [Content Brief]
- [2]. Rohlfing AE, et al. Polyphosphate Kinase Antagonizes Virulence Gene Expression in Francisella tularensis. J Bacteriol. 2018;200(3):e00460-17. Published 2018 Jan 10. [Content Brief]
Keywords
