Polyphosphate kinase
Polyphosphate kinase (RsPPK; PPK) is a key enzyme in bacteria that catalyzes the reversible conversion between inorganic polyphosphate (polyP) and nucleoside phosphates (ATP/ADP/AMP, etc.). Polyphosphate kinase antagonizes the expression of virulence genes regulated by (p) ppGpp, PigR, MglA and SspA in Francisella tularensis. Polyphosphate kinase can be used in studies related to tularemia.
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- CAS No.: 9026-44-2
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Polyphosphate kinase exhibits strong ATP-dependent polyphosphate (polyP) synthesis activity in vitro in the presence of an ATP regeneration system, and it can phosphorylate ADP and GDP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9026-44-2
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SMILES
[Polyphosphate kinase]
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Synonyms
RsPPK; PPK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Neville N, et al. Polyphosphate Kinase 2 (PPK2) Enzymes: Structure, Function, and Roles in Bacterial Physiology and Virulence. Int J Mol Sci. 2022;23(2):670. Published 2022 Jan 8. [Content Brief]
[2]. Rohlfing AE, et al. Polyphosphate Kinase Antagonizes Virulence Gene Expression in Francisella tularensis. J Bacteriol. 2018;200(3):e00460-17. Published 2018 Jan 10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polyphosphate kinase Related Classifications
HY-E70426 Related Classifications
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