90357-63-4
90357-63-4
Chemical Structure
Brickellin
- CAS No.: 90357-63-4
- Formula:C20H20O9
- Molecular Weight:404.37
IUPAC Name: 5-hydroxy-2-(2-hydroxy-4,5-dimethoxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one
InChIKey: USWPTYUGAMOLAB-UHFFFAOYSA-N
SMILES: O=C1C(OC)=C(OC2=CC(OC)=C(OC)C(O)=C12)C=3C=C(OC)C(OC)=CC3O
Biological Activity: Brickellin is an antioxidant agent that can be isolated from Varronia curassavica Jacq.. Brickellin inhibits advanced glycation end products (AGEs) formation, protein crosslinking, and oxidative damage to proteins. Brickellin can be used for the research of diabetes[1][2][3].
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Brickellin | Brickellin is an antioxidant agent that can be isolated from Varronia curassavica Jacq.. Brickellin inhibits advanced glycation end products (AGEs) formation, protein crosslinking, and oxidative damage to proteins. Brickellin can be used for the research of diabetes. | |||||||||||||||||||||
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References
- [1]. Arisawa M, et al. Isolation and cytotoxicity of two new flavonoids from Chrysosplenium grayanum and related flavonols. J Nat Prod. 1991;54(3):898-901. [Content Brief]
- [2]. Rodrigues WD, et al. In Vitro Antiglycation Potential of Erva-Baleeira (Varronia curassavica Jacq.). Antioxidants (Basel). 2023 Feb 19;12(2):522. [Content Brief]
- [3]. Kubra B, Badshah SL, Faisal S, Sharaf M, Emwas AH, Jaremko M, Abdalla M. Inhibition of the predicted allosteric site of the SARS-CoV-2 main protease through flavonoids. J Biomol Struct Dyn. 2023 Oct-Nov;41(18):9103-9120. [Content Brief]
Keywords
