944795-06-6
944795-06-6
Chemical Structure
Lck inhibitor 2
- CAS No.: 944795-06-6
- Formula:C18H17N5O2
- Molecular Weight:335.36
IUPAC Name: 3-((4-((5-hydroxy-2-methylphenyl)amino)pyrimidin-2-yl)amino)benzamide
InChIKey: SFCBIFOAGRZJNX-UHFFFAOYSA-N
SMILES: OC1=CC=C(C)C(NC2=CC=NC(NC3=CC(C(N)=O)=CC=C3)=N2)=C1
Biological Activity: Lck inhibitor 2 is a bisanilino pyrimidine-derived tyrosine kinase inhibitor targeting LCK, BTK, LYN, SYK and TXK, with a Kd value of 10 nM against TXK[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lck inhibitor 2 | 99.73% | Lck inhibitor 2 is a bisanilino pyrimidine-derived tyrosine kinase inhibitor targeting LCK, BTK, LYN, SYK and TXK, with a Kd value of 10 nM against TXK. | ||||||||||||||||||||
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Lck inhibitor 2 (Standard) | ≥98% | Lck inhibitor 2 (Standard) is the analytical standard of Lck inhibitor 2 (HY-10644). This product is intended for research and analytical applications. Lck inhibitor 2 is a multi-target tyrosine kinase inhibitor with IC50s of 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-15737DB07268 -
Similarity Score 0.75
HY-160688GW759710A -
Similarity Score 0.61
HY-14266Dapivirine -
Similarity Score 0.61
HY-14266ADapivirine hydrochloride -
Similarity Score 0.60
HY-16420R112 -
Similarity Score 0.59
HY-164454AJI-100 -
Similarity Score 0.59
HY-10574ARilpivirine hydrochloride -
Similarity Score 0.59
HY-10574Rilpivirine -
Similarity Score 0.59
HY-167642(Z)-Rilpivirine -
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