94666-15-6
Chemical Structure
(-)-Amosulalol
Synonym(s): (-)-YM 09538
- CAS No.: 94666-15-6
- Formula:C18H24N2O5S
- Molecular Weight:380.46
InChIKey: LVEXHFZHOIWIIP-HNNXBMFYSA-N
SMILES: O=S(C1=CC([C@@H](O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O
Biological Activity: (-)-Amosulalol ((-)-YM 09538) is an isomer of Amosulalol (HY-106720), an orally active dual inhibitor of α1/β1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting α1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting β1-adrenergic receptors.
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(-)-Amosulalol | (-)-Amosulalol ((-)-YM 09538) is an isomer of Amosulalol (HY-106720), an orally active dual inhibitor of α1/β1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting α1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting β1-adrenergic receptors. | |||||||||||||||||||||
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