CBR Agonist-2
CBR Agonist-2 is a CB1 agonist (CB1R; CB1 ligand) with an EC50 and a Ki of 960 nM and 970 nM, respectively. CBR Agonist-2 is a promising tool for investigating the involvement of hCB1R in disorders associated with the endocannabinoid system.
For research use only. We do not sell to patients.
- Formula: C27H27FN4O
- Molecular Weight:442.53
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
hCB1-R 960 nM (EC50) |
hCB1-R 970 nM (Ki) |
CBR Agonist-2 (10 nM-1 μM; 24 hours) induces ERK1/2 activation in a dose-dependent manner in CHO cells expressing Gαq16 and hCB1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:CHO cells expressing Gαq16 and hCB
-
Concentration:10 nM; 100 nM; 1000 nM
-
Incubation Time:24 Hours
-
Result:Increased dose-dependent phosphorylation of ERK1/2 (pERK1/2) after CB1R stimulation by CBR Agonist-2.
Chemical Information
-
Molecular Weight 442.53
-
Formula C27H27FN4O
-
SMILES
O=C(C1=CN(C2=CC=CC=C12)CCCCCF)NCC3=CC=CC=C3/N=N/C4=CC=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CBR Agonist-2 Related Classifications
HY-151107 Related Classifications
Powered by Bioz