AM4085
AM4085 is an orally active Antagonist for FmlH with an IC50 of 0.19 μM. AM4085 reveals metabolic stability in mouse liver microsomes and blood plasma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C21H21F4NO6
- Molecular Weight:459.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Pharmacokinetic Analysis of AM4085 in C3H/HeN mice[1]
| route | Dose (mg/kg) | C0 (ng/mL) | Cmax (ng/mL) | T1/2 (h) | Vdss (L/kg) | CL (mL/min/kg) | Tlast (h) | AUC0-last (ng·h/mL) | AUC0-inf (ng·h/mL) | MRT0-last (h) | MRT0-inf (h) | AUCExtra (%) | AUMCExtra (%) | F (%) |
| iv | 3 | 4427 | - | 1.47 | 1.42 | 13.6 | 8.0 | 3662 | 3736 | 1.59 | 1.75 | 1.90 | 10.8 | - |
| po | 10 | - | 1483 | 1.92 | - | - | 8.0 | 6070 | 6564 | 3.18 | 3.75 | 7.55 | 21.6 | 52.7 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 459.39
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Formel C21H21F4NO6
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SMILES
FC1=CC=C(C2=C(C(F)(F)F)C=CC=C2O[C@@H]3O[C@H](CO)[C@H](O)[C@@H](O)[C@H]3NC(C)=O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AM4085 Related Classifications
HY-163291 Related Classifications
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