910232-84-7
910232-84-7
Chemical Structure
CGI-1746
- CAS. Nr.: 910232-84-7
- Formula:C34H37N5O4
- Molecular Weight:579.69
IUPAC Name: 4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide
InChIKey: JIFCFQDXHMUPGP-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)C(C)(C)C)NC2=CC=CC(C(N=C3NC4=CC=C(C=C4)C(N5CCOCC5)=O)=CN(C3=O)C)=C2C
Biological Activity: CGI-1746 is a potent and highly selective inhibitor of the Btk with IC50 of 1.9 nM.
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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CGI-1746 | 99.25% | CGI-1746 is a potent and highly selective inhibitor of the Btk with IC50 of 1.9 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.90
HY-168292BTK ligand 9 -
Similarity Score 0.67
HY-101521CHMFL-BTK-01 -
Similarity Score 0.61
HY-15427GDC-0834 -
Similarity Score 0.61
HY-15427AGDC-0834 Racemate -
Similarity Score 0.61
HY-15427BGDC-0834 (S-enantiomer) -
Similarity Score 0.58
HY-122830DD-03-171 -
Similarity Score 0.53
HY-18016CGI 560 -
Similarity Score 0.50
HY-153500Hedgehog IN-4 -
Similarity Score 0.50
HY-117499RN941 -
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