Prnd - prion like protein doppel Gene

Also Known as Dpl; PrPLP; doppel

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26434

Summary

Enables copper ion binding activity. Involved in acrosome reaction. Acts upstream of or within cellular copper ion homeostasis. Is anchored component of external side of plasma membrane. Is expressed in several structures, including embryo mesenchyme; gut; heart; nervous system; and testis. Orthologous to human PRND (prion like protein doppel). [provided by Alliance of Genome Resources, Apr 2022]

Prnd Products (4)

mRNA Protein Name
NM_001126338.2 NP_001119810.1 prion-like protein doppel precursor
NM_001278257.1 NP_001265186.1 prion-like protein doppel precursor
NM_001278520.1 NP_001265449.1 prion-like protein doppel precursor
NM_023043.3 NP_075530.1 prion-like protein doppel precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables copper ion binding IDA
IDA: Inferred from direct assay
12482851 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24225951 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in acrosome reaction IMP
IMP: Inferred from mutant phenotype
15161660 MGI
acts upstream of or within intracellular copper ion homeostasis IDA
IDA: Inferred from direct assay
12482851 MGI
involved in single fertilization IMP
IMP: Inferred from mutant phenotype
12110578 MGI
NOT involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
15161660 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
10842180 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prion-like protein doppel

  • doppelganger

  • prion protein dublet

  • prion protein-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-183849 H9-KGDEVD-MMAE Ligand / Unkown
HY-RS11187 PRND Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22287 Prnd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28810 Prnd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prnd NCBI NCBI:23627