RPS9 - ribosomal protein S9 Gene
Also Known as S9
Species: Homo sapiens
About RPS9
This gene has 13 transcripts (splice variants), 1 gene allele and 190 orthologues. Ubiquitous expression in ovary (RPKM 603.9), bone marrow (RPKM 379.2) and 25 other tissues.
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008]
RPS9 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001013.4 | NP_001004.2 | 40S ribosomal protein S9 isoform a |
| NM_001321701.2 | NP_001308630.1 | 40S ribosomal protein S9 isoform a |
| NM_001321702.2 | NP_001308631.1 | 40S ribosomal protein S9 isoform a |
| NM_001321704.2 | NP_001308633.1 | 40S ribosomal protein S9 isoform a |
| NM_001321705.2 | NP_001308634.1 | 40S ribosomal protein S9 isoform b |
| NM_001321706.2 | NP_001308635.1 | 40S ribosomal protein S9 isoform c |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
18420587 | GOA |
| enables structural constituent of ribosome |
IDA
IDA: Inferred from direct assay
|
23636399 | GOA |
| enables translation regulator activity |
IMP
IMP: Inferred from mutant phenotype
|
18420587 | GOA |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in positive regulation of cell population proliferation |
IMP
IMP: Inferred from mutant phenotype
|
18420587 | GOA |
| involved in ribosomal small subunit biogenesis |
IDA
IDA: Inferred from direct assay
|
34516797 | GOA |
| involved in translation |
IMP
IMP: Inferred from mutant phenotype
|
18420587 | GOA |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
18420587 | GOA |
| located in cytosolic ribosome |
IDA
IDA: Inferred from direct assay
|
23636399 | GOA |
| part of cytosolic small ribosomal subunit |
IDA
IDA: Inferred from direct assay
|
8706699 | GOA |
| located in nucleolus |
IDA
IDA: Inferred from direct assay
|
18420587 | GOA |
| part of ribonucleoprotein complex |
IDA
IDA: Inferred from direct assay
|
17289661 | GOA |
| part of small-subunit processome |
IDA
IDA: Inferred from direct assay
|
34516797 | GOA |
RPS9 Protein Structure
Ribosomal_S4: Ribosomal protein S4/S9 N-terminal domain (7 - 107)
S4: S4 domain (108 - 151)
- 0
- 100
- 194 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
40S ribosomal protein S9 |
|
RPS9 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
RPS9 | P46781 | RPS2 | Homo sapiens | P15880 | 30021884 | |
|
Intra
|
RPS9 | P46781 | STAT3 | Homo sapiens | P40763 | 21988832 |
RPS9 Antibodies
| Art. -Nr. | Produktname | Anwendung | Reactivity |
|---|---|---|---|
| HY-P810922 | RPS9 Antibody | WB, IHC-P, ICC/IF, FC | Human, Mouse, Rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Takayasu Arteritis |
|
|
| Diamond-Blackfan Anemia |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | RPS9 | RGD | RGD:619889 |
| Felis catus | RPS9 | VGNC | VGNC:64762 |
| Mus musculus | RPS9 | MGD | MGI:1924096 |
| Canis familiaris | RPS9 | VGNC | VGNC:45749 |
| Macaca mulatta | RPS9 | VGNC | VGNC:76936 |
| Bos taurus | RPS9 | VGNC | VGNC:34152 |
| Others | RPS9 | NCBI |