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Ibrilparant

Ibrilparant is a LPA1 receptor antagonist with an IC₅₀ of 0.00753 μM. Ibrilparant exhibits LPA1 calcium flux antagonistic activity, with an IC₅₀ of 3.02 nM. Ibrilparant can be used in research related to various diseases such as cancer and inflammatory diseases.

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CAS. Nr.: 2978107-47-8
Formel: C₂₅H₃₁NO₅
Molecular Weight:425.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ibrilparant Chemical Structure

CAS. Nr.: 2978107-47-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

LPA₁ Receptor

In Vitro

Ibrilparant (compound 355) exerts potent functional antagonistic activity against LPA1 in CHO-K1 cells overexpressing human LPA1 and G15a, with an IC₅₀ of 0.00753 μM^[1].
Ibrilparant exhibits potent LPA1 calcium flux antagonistic activity in CHO-K1 cells overexpressing human LPA1 and G15a, with an IC₅₀ of 3.02 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2978107-47-8
Molecular Weight 425.52
Formel C₂₅H₃₁NO₅
SMILES

O=C(C1(CCOCC1)NC2=CC=C(C(COC3CC3)=C2)C4=C(C)C(OCC)=CC=C4)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Huang W, et al. Compounds and compositions for treating conditions associated with lpa receptor activity. WO2023160672A1. WIPO; 2023 Aug 31.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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