Indolaprilat
Indolaprilat is an ACE inhibitor with an IC50 value of 3.0 nM. Indolaprilat also inhibits aminopeptidase P, with an IC50 of 485 μM for aminopeptidase P. Indolaprilat inhibits the zinc metallopeptidase-mediated cleavage of angiotensin I, Bradykinin (HY-P0206), and proline-containing oligopeptides. Indolaprilat can be used in related research on hypertension and congestive heart failure.
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- CAS. Nr.: 80828-34-8
- Formel: C22H30N2O5
- Molecular Weight:402.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
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ACE 3 nM (IC50) |
aminopeptidase P 485 μM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 80828-34-8
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Molecular Weight 402.48
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Formel C22H30N2O5
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SMILES
OC([C@H](CCC1=CC=CC=C1)N[C@@H](C)C(N2[C@]3([H])[C@](CCCC3)([H])C[C@H]2C(O)=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)