Lipid TD5
Based on 1 Customer Validation
Lipid TD5 is an ionizable cationic lipid with a pKa value of 7.3. Lipid TD5 can be used to prepare lipid nanoparticles (LNPs), which efficiently deliver mRNA and the CRISPR/Cas9 system to the central nervous system and enable their expression.
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- Reinheit : 99.19%
- CAS. Nr.: 2855180-86-6
- Formel: C45H81N3O
- Molecular Weight:680.16
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biologische Aktivität
Beschreibung
In Vitro
TD5 BLNPs enter primary mouse astrocytes mainly via 5-HT1A receptor-mediated endocytosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2855180-86-6
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Appearance Oil
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Molecular Weight 680.16
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Formel C45H81N3O
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Color White to light yellow
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SMILES
O=C(NCCCCCCN(CCCCCCCCCCCCCC)CCCCCCCCCCCCCC)CCC1=CNC=2C=CC=CC21
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 5 mg/mL (7.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
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Topics Lipid Nanoparticles: Key Nucleic Acid Delivery Vectors
Lipid nanoparticles (LNPs) are the most clinically advanced non-viral delivery systems for nucleic acid therapeutics and enable the in vivo delivery of mRNA, siRNA, and other genetic cargos.
2026-06-18
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4702 mL | 7.3512 mL | 14.7024 mL | 36.7561 mL |
| 5 mM | 0.2940 mL | 1.4702 mL | 2.9405 mL | 7.3512 mL |