country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-143288

Copy Link Print Information

NTPDase2-IN-1

NTPDase2-IN-1 is a non-competitive, selective NTPDase2 inhibitor, with an IC₅₀ of 0.04 μM against h-NTPDase2 and an IC₅₀ of 2.27 μM against h-NTPDase8. NTPDase2-IN-1 is applicable for cancer-related research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2883147-47-3
Formel: C₂₄H₂₀FN₃OS₂
Molecular Weight:449.56

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NTPDase2-IN-1 Chemical Structure

CAS. Nr.: 2883147-47-3

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

h-NTPDase-2

0.04 μM (IC₅₀)

h-NTPDase-8

2.27 μM (IC₅₀)

Alle NTPDase Isoform-spezifische Produkte anzeigen :

In Vitro

NTPDase2-IN-1 (Compound 5g) (100 μM; 15 min) exhibits an inhibition rate of 42% against recombinant h-NTPDase1 at a concentration of 100 μM^[1].
NTPDase2-IN-1 (15 min) potently inhibits recombinant h-NTPDase2, with an IC₅₀ value of 0.04 μM^[1].
NTPDase2-IN-1 (100 μM; 15 min) inhibits 28% of recombinant h-NTPDase3 at a concentration of 100 μM^[1].
NTPDase2-IN-1 (15 min) inhibits recombinant h-NTPDase8 with an IC₅₀ value of 2.27 μM^[1].
NTPDase2-IN-1 (0.02-0.08 μM) acts as a non-competitive inhibitor of recombinant h-NTPDase2, which reduces V_max without altering K_m^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2883147-47-3
Molecular Weight 449.56
Formel C₂₄H₂₀FN₃OS₂
SMILES

CC(C1=CC=C(C(F)=C1)C2=CC=CC=C2)C(NC3=NN=C(S3)SCC4=CC=CC=C4)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Abbas S, et al.. Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors. Bioorganic chemistry. 2022 Jan;118:105456. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen

Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

NTPDase2-IN-1

Alle NTPDase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

NTPDase2-IN-1 Related Classifications

HY-143288 Related Classifications

Bioz

Keywords

Your Recently Viewed Products

IC₅₀ & Target