Parsaclisib (Standard)
Parsaclisib (Standard) is the analytical standard of Parsaclisib (HY-109068). This product is intended for research and analytical applications. Parsaclisib (INCB050465) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib can be used for the research of relapsed or refractory B-cell malignancies.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1426698-88-5
- Formel: C20H22ClFN6O2
- Molecular Weight:432.88
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-109068
ParsaclisibPI3Kδ Inhibitor -
HY-17044
DuvelisibPI3Kδ Inhibitor -
HY-100716
EganelisibPI3Kγ Inhibitor -
HY-15868
HS-173PI3Kα Inhibitor -
HY-12644
AcalisibPI3K Inhibitor -
HY-17044R
Duvelisib (Standard)PI3Kδ Inhibitor -
HY-12030
PIK-90PI3K Inhibitor -
HY-13531
AS-604850PI3Kγ Inhibitor -
HY-118521
AS-041164PI3Kγ Inhibitor -
HY-100716R
Eganelisib (Standard)PI3Kγ Inhibitor -
HY-19535
Nemiralisib hydrochloride
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 1426698-88-5
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Molecular Weight 432.88
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Formel C20H22ClFN6O2
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SMILES
CCOC1=C([C@@H](C2)CNC2=O)C(F)=C(Cl)C=C1[C@@H](N3C4=NC=NC(N)=C4C(C)=N3)C
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Synonyms
INCB050465 (Standard); IBI-376 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[2]. Shin N, et, al. Parsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell Malignancy. J Pharmacol Exp Ther. 2020 Jul;374(1):211-222. [Content Brief]
[3]. Yue EW, et, al. INCB050465 (Parsaclisib), a Novel Next-Generation Inhibitor of Phosphoinositide 3-Kinase Delta (PI3Kδ). ACS Med Chem Lett. 2019 Oct 17;10(11):1554-1560. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Parsaclisib (Standard) Related Classifications
HY-109068R Related Classifications
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