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Art. -Nr.: HY-130576

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POVPC

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POVPC is an oxidized phospholipid can be found in in oxidatively modified low density lipoprotein (oxLDL). POVPC inhibits VSMC growth in high serum condition. POVPC induces apoptosis in low serum condition.

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Reinheit: 99.9%
CAS. Nr.: 121324-31-0
Formel: C₂₉H₅₆NO₉P
Molecular Weight:593.73

Speicherung:

Solution, -20°C, 2 years

POVPC Chemical Structure

CAS. Nr.: 121324-31-0

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

POVPC (0-100 µM; 13 h) inhibits VSMC growth in a dose-dependent manner^[1].
POVPC (50 µM; 2, 4, 6 h) induces apoptosis in a time-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

vascular smooth muscle cells (VSMC)
Concentration:

0-100 µM (under high serum conditions (10% FCS))
Incubation Time:

13 h
Result:

Inhibited VSMC growth in a dose-dependent manner.

Apoptosis Analysis^[1]

Cell Line:

7r5 cells
Concentration:

50 µM (0.1% FCS)
Incubation Time:

2, 4, 6 h
Result:

Induced apoptosis in a time-dependent manner.

Chemical Information

CAS. Nr. 121324-31-0
Appearance Liquid
Molecular Weight 593.73
Formel C₂₉H₅₆NO₉P
Color Colorless to light yellow
SMILES

C[N+](C)(C)CCOP(OC[C@H](OC(CCCC=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Solution, -20°C, 2 years

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Fruhwirth GO, et al. The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 2006 Sep;1761(9):1060-9. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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