Antibacterial compounds from the leaves of Acanthopanax senticosus

  • Arch Pharm Res. 2003 Jan;26(1):40-2. doi: 10.1007/BF03179929.
Sanghyun Lee  1 ,  Dong-Sun Shin ,  Ki-Bong Oh ,  Kuk Hyun Shin
Affiliations
  • 1. Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
PMID: 12568356 DOI: 10.1007/BF03179929
Abstract

Chiisanogenin (1), hyperin (2) and chiisanoside (3) were isolated from the leaves of Acanthopanax senticosus, and were tested for their inhibitory activities against 6 strains of bacteria. Among them, chiisanogenin (1) revealed broad but moderate Antibacterial activities against G (+) and G (-) bacteria, the minimum inhibitory concentration (MIC) being in the range of 50-100 microg/ml.

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