RY 024
RY 024 is an active compound.
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- CAS. Nr.: 173990-15-3
- Formel: C19H19N3O3
- Molecular Weight:337.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | EC50 |
324.4 μM
Compound: RY-024
|
Activity at alpha-4-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-4-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
51.7 μM
Compound: RY-024
|
Activity at alpha-6-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-6-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
74.4 μM
Compound: RY-024
|
Activity at GABAA alpha-1-beta-3-gamma-2 receptor expressed in Xenopus oocytes assessed as inhibition of GABA-induced current by voltage clamp assay
Activity at GABAA alpha-1-beta-3-gamma-2 receptor expressed in Xenopus oocytes assessed as inhibition of GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
9.8 μM
Compound: RY-024
|
Activity at alpha-5-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-5-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
95.5 μM
Compound: RY-024
|
Activity at alpha-2-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-2-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
Chemical Information
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CAS. Nr. 173990-15-3
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Molecular Weight 337.37
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Formel C19H19N3O3
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SMILES
O=C(OC(C)(C)C)C1=C(CN2C)N(C3=CC=C(C=C3C2=O)C#C)C=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)