Tapcin
Tapcin is a dual inhibitor for topoisomerase I and topoisomerase II, with IC50 of 203 and 71 nM. Tapcin inhibits proliferations of cancer cells A-375, HeLa, Huh7.5, U2-OS, A549, Caco-2 and HT29, with IC50s of 441, 1.04, 40.5, 0.002, 0.006, 0.287 and 0.842 nM, respectively. Tapcin exhibits antitumor activity in HT29 xenograft model.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C64H73N11O13S3
- Molecular Weight:1300.53
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Topoisomerase Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
IC50 & Target
|
Topoisomerase II 71 nM (IC50) |
Topoisomerase I 203 nM (IC50) |
Chemical Information
-
Molecular Weight 1300.53
-
Formel C64H73N11O13S3
-
SMILES
O=C([C@H](C)NC([C@H](C)NC(CC(O)CCCCCCCCCCC)=O)=O)NC1=CC=C(C2=NC(C3=NC(C4=NC(C(N[C@H](C(NC5=CC=C(C(NC6=C(OC(C)C)C(O)=C(C(NC7=CC=C(C(O)=O)C=C7)=O)C=C6)=O)C=C5)=O)CC(N)=O)=O)=CS4)=CS3)=CS2)C=C1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Tapcin Related Classifications
HY-161628 Related Classifications
Powered by Bioz