TLR7 agonist 19
TLR7 agonist 19 (Compound 14) is a Toll-like receptor 7 (TLR7) agonist with excellent pharmacokinetic properties and synergistic antitumor activity.
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- CAS. Nr.: 2682008-42-8
- Formel: C28H42N8O3
- Molecular Weight:538.68
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| T-cell | IC50 |
>25 μM
Compound: 14
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Cytotoxicity against PHA-activated T-cells (unknown origin) assessed as inhibition of IL-2 induced cell proliferation measured after 72 hrs by MTS assay
Cytotoxicity against PHA-activated T-cells (unknown origin) assessed as inhibition of IL-2 induced cell proliferation measured after 72 hrs by MTS assay
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[PMID: 38352849] |
Chemical Information
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CAS. Nr. 2682008-42-8
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Molecular Weight 538.68
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Formel C28H42N8O3
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SMILES
CCC[C@H](NC1=C(N(CC2=NC=C(C3CCN(C4CCOCC4)CC3)C=C2OC)N=C5)C5=NC(N)=N1)CCO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TLR7 agonist 19 Related Classifications
HY-162163 Related Classifications
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