Trevotamig
Based on 1 Customer Validation
HY-P991034 is an EPCAM/CD3E-targeting H-γ1_L-κ-scFvhl dimer type bispecific antibody.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 95.539%
- CAS. Nr.: 2920215-79-6
- Molecular Weight:199.186 kDa
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
H-gamma1_L-kappa-scFvhl dimer
Human
EPCAM & CD3E
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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H-gamma1_L-kappa-scFv(heavy-lambda)
ELISA, FACS, Functional assay
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Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Trevotamig. The EC50 for this effect is 110.3 ng/mL. -
Immobilized EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P72367) can bind Trevotamig. The EC50 for this effect is 46.09 ng/mL. -
Flow Cytometry analysis of Jurkat cells labelling CD3E (red) with Trevotamig (anti-CD3E) (HY-P991034). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black). -
Flow Cytometry analysis of Hela cells labelling EPCAM (red) with Trevotamig (anti-EPCAM) (HY-P991034). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS. Nr. 2920215-79-6
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Appearance Liquid
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Molecular Weight 199.186 kDa
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Color Colorless to light yellow
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SMILES
[Trevotamig]
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Versand
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (254 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)