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Art. -Nr.: HY-182451

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V11294

V11294 is a phosphodiesterase 4 (PDE4) inhibitor with a K_i value of 436 nM against human lung PDE4. V11294 exhibits anti-inflammation activity.

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CAS. Nr.: 162278-10-6
Formel: C₂₃H₃₁N₅O₂
Molecular Weight:409.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

V11294 Chemical Structure

CAS. Nr.: 162278-10-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

V11294 is a phosphodiesterase 4 (PDE4) inhibitor with a K_i value of 436 nM against human lung PDE4. V11294 exhibits anti-inflammation activity^[1].

IC₅₀ & Target^[1]

hPDE4D

436 nM (Ki)

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen :

In Vitro

V11294 (Compound 34) selectively inhibits human lung hPDE4 with a K_i of 436 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 162278-10-6
Molecular Weight 409.52
Formel C₂₃H₃₁N₅O₂
SMILES

CCNC1=C2N=C(C(C)C)N=C2N(CC3=CC=C(C(OC4CCCC4)=C3)OC)C=N1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Kodimuthali A, et al. Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. J Med Chem. 2008 Sep 25;51(18):5471-89. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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V11294

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen