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Art. -Nr.: HY-116469

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ZP7

ZP7 (compound 7c) is a potent anti-HIV-1 agent with an EC₅₀ of 36.4nM. ZP7 can be utilized in HIV-1 research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1188890-60-9
Formel: C₁₅H₉Br₂ClN₄OS₂
Molecular Weight:520.65

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

ZP7 Chemical Structure

CAS. Nr.: 1188890-60-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

ZP7 (compound 7c) is a potent anti-HIV-1 agent with an EC₅₀ of 36.4nM. ZP7 can be utilized in HIV-1 research^[1].

Alle HIV Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
MT4	CC₅₀	>240.08 μM Compound: 7c	Cytotoxicity against human MT4 cells after 5 days by MTT assay Cytotoxicity against human MT4 cells after 5 days by MTT assay	[PMID: 19620009]
MT4	EC₅₀	>240.08 μM Compound: 7c	Antiviral activity against HIV2 ROD infected in human MT4 cells after 5 days by MTT assay Antiviral activity against HIV2 ROD infected in human MT4 cells after 5 days by MTT assay	[PMID: 19620009]
MT4	EC₅₀	0.0364 μM Compound: 7c	Antiviral activity against HIV1 3B infected in human MT4 cells after 5 days by MTT assay Antiviral activity against HIV1 3B infected in human MT4 cells after 5 days by MTT assay	[PMID: 19620009]
MT4	EC₅₀	36.4 μM Compound: ZP7	Antiviral activity against HIV-1 3B infected human MT4 cells assessed as inhibition in viral syncytium formation by MTT assay Antiviral activity against HIV-1 3B infected human MT4 cells assessed as inhibition in viral syncytium formation by MTT assay	[PMID: 22883027]

Chemical Information

CAS. Nr. 1188890-60-9
Molecular Weight 520.65
Formel C₁₅H₉Br₂ClN₄OS₂
SMILES

O=C(CSC1=C(C2=C(Br)C=C(Br)C=C2)N=NS1)NC3=CC=CN=C3Cl
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Zhan P, et al. Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies. Bioorg Med Chem. 2009 Aug 15;17(16):5920-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
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Chemical Information
Reinheit & Dokumentation
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ZP7

Alle HIV Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

ZP7 Related Classifications

HY-116469 Related Classifications