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Cat. No.: HY-P11946

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C3.15

C3.15 is a gallium-binding agent and a weak arsenic-binding agent. C3.15 is also a gallium-binding phage clone with the peptide sequence NYPLHQSSSPSR. The binding capacity of C3.15 for gallium (III) ions is significantly higher at pH 8.5 than at pH 3.2, and its arsenic binding amount remains extremely low at both pH values. Compared with wild-type phage, the arsenic biosorption capacity of C3.15 is greatly reduced at pH 8.5.

For research use only. We do not sell to patients.

Formula: C₅₈H₈₉N₁₉O₂₀
Molecular Weight:1372.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

C3.15 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Bacteriophage clone C3.15 (2.7-2.8 mM Ga³⁺; 2.6-3.1 mM As³⁺; 1.2-1.5 mM Ga³⁺ + 1.3-1.4 mM As³⁺; 16-18 h) selectively binds gallium over arsenic, with 2.21-fold higher gallium biosorption than wild-type at pH 8.5 and minimal arsenic binding (0.27-fold higher than wild-type) at the same pH^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 1372.44
Formula C₅₈H₈₉N₁₉O₂₀
SMILES

O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CO)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N
Sequence

Asn-Tyr-Leu-Pro-His-Gln-Ser-Ser-Ser-Pro-Ser-Arg
Sequence Shortening

NYLPHQSSSPSR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Schönberger N, et al. Directed Evolution and Engineering of Gallium-Binding Phage Clones-A Preliminary Study. Biomimetics (Basel, Switzerland). 2019 May 08;4(2):35. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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