AM-6226

AM-6226 is a potent and orally active G protein coupled receptor 40 (GPR40) full agonist with an EC50 of 0.12 μM. AM-6226 can activate the GPR40 receptors on pancreatic β cells and enteroendocrine L cells, promote insulin secretion in a glucose-dependent manner and also increase the release of incretin hormones (GLP-1, GIP), thereby avoiding the risk of hypoglycemia. AM-6226 can be used for the research of metabolic disease, such as diabetes.

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  • CAS No.: 1449742-87-3
  • Formule: C32H36F2O4
  • Masse moléculaire:522.62
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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