Bonaphthone
Bonaphthone is an antiviral agent with anti-DNA and -RNA viral activities.
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- CAS No.: 6954-48-9
- Formule: C10H5BrO2
- Masse moléculaire:237.05
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
Chemical Information
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CAS No. 6954-48-9
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Appearance Solid
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Masse moléculaire 237.05
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Formule C10H5BrO2
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Color Yellow to brown
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SMILES
C1=CC(=O)C(=O)C2=CC=C(C=C12)Br
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 125 mg/mL (527.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
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Fiche technique (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2185 mL | 21.0926 mL | 42.1852 mL | 105.4630 mL |
| 5 mM | 0.8437 mL | 4.2185 mL | 8.4370 mL | 21.0926 mL | |
| 10 mM | 0.4219 mL | 2.1093 mL | 4.2185 mL | 10.5463 mL | |
| 15 mM | 0.2812 mL | 1.4062 mL | 2.8123 mL | 7.0309 mL | |
| 20 mM | 0.2109 mL | 1.0546 mL | 2.1093 mL | 5.2731 mL | |
| 25 mM | 0.1687 mL | 0.8437 mL | 1.6874 mL | 4.2185 mL | |
| 30 mM | 0.1406 mL | 0.7031 mL | 1.4062 mL | 3.5154 mL | |
| 40 mM | 0.1055 mL | 0.5273 mL | 1.0546 mL | 2.6366 mL | |
| 50 mM | 0.0844 mL | 0.4219 mL | 0.8437 mL | 2.1093 mL | |
| 60 mM | 0.0703 mL | 0.3515 mL | 0.7031 mL | 1.7577 mL | |
| 80 mM | 0.0527 mL | 0.2637 mL | 0.5273 mL | 1.3183 mL | |
| 100 mM | 0.0422 mL | 0.2109 mL | 0.4219 mL | 1.0546 mL |
Bonaphthone Related Classifications
HY-W269306 Related Classifications
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